• Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort 

      Vatne, Anlaug; Hapnes, Nina; Stensvold, Hans Jørgen; Dalen, Ingvild; Guthe, Hans Jørgen Timm; Støen, Ragnhild; Brigtsen, Anne Karin; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)
      Objective The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until discharge.<p> <p>Study design Population-based, nationwide registry study in Norway including all live-born infants with a gestational age <32 weeks surviving first postnatal week without ...
    • Early-Onset Sepsis in Neonates - A Population-Based Study in South-West Norway From 1996 to 2018 

      Vatne, Anlaug; Klingenberg, Claus; Rettedal, Siren; Øymar, Knut Asbjørn Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i>: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy strategies.<br><br> <i>Objectives</i>: To describe the incidence of culture-confirmed EOS, causative pathogens, antibiotic susceptibility patterns and antibiotic therapy ...
    • Late-onset sepsis in very preterm infants in Norway in 2009-2018: A population-based study 

      Huncikova, Zuzana; Vatne, Anlaug; Stensvold, Hans Jørgen; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Salvesen, Bodil; Øymar, Knut Asbjørn Alexander; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Objective To evaluate epidemiology and outcomes among very preterm infants (<32 weeks’ gestation) with culture-positive and culture-negative late-onset sepsis (LOS).<p> <p>Design Cohort study using a nationwide, population-based registry. <p>Setting 21 neonatal units in Norway. <p>Participants All very preterm infants born 1 January 2009–31 December 2018 and admitted to a neonatal ...
    • Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care 

      Norman, Mikael; Padkær Petersen, Jesper; Stensvold, Hans Jørgen; Thorkelsson, Thordur; Helenius, Kjell; Brix Andersson, Charlotte; Ørum Cueto, Heidi; Domellöf, Magnus; Gissler, Mika; Heino, Anna; Håkansson, Stellan; Jonsson, Baldvin; Klingenberg, Claus Andreas; Lehtonen, Liisa; Metsäranta, Marjo; Rønnestad, Arild Erland; Trautner, Simon; Vatne, Anlaug; Støen, Ragnhild; Brække, Kristin; Reigstad, Hallvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-13)
      Aim - Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis.<p> <p>Methods - Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm ...
    • Variation in antibiotic consumption in very preterm infants-a 10 year population-based study 

      Huncikova, Zuzana; Stensvold, Hans Jørgen; Øymar, Knut Asbjørn Alexander; Vatne, Anlaug; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Moster, Dag; Eriksen, Beate Horsberg; Selberg, Terje Reidar; Rønnestad, Arild Erland; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-21)
      Objectives: Wide variations in antibiotic use in very preterm infants have been reported across centres despite similar rates of infection. We describe 10 year trends in use of antibiotics and regional variations among very preterm infants in Norway. Patients and Methods: All live-born very preterm infants (<32 weeks gestation) admitted to any neonatal unit in Norway during 2009–18 were included. ...